SpLitteR is a tool that uses linked reads to improve the contiguity of HiFi assemblies. Given a linked-read library and a HiFi assembly graph in the GFA format, SpLitteR resolves repeats in the assembly graph using linked-reads and generates a simplified (more contiguous) assembly graph with corresponding scaffolds.


SpLitteR is implemented on top of SPAdes and will be available soon as a part of SPAdes package. For now, one can download, build, and try a pre-release version of SPAdes package including SpLitteR.


In case of any questions, suggestions, bug reports, please write to  or directly to Ivan Tolstoganov.


If you have a problem running BinSPreader you can look for a similar issue on our GitHub repository, create a new one or write us via e-mail: .