The T2T consortium presented the complete linear assembly of human chromosome 8 that resolves five previously long-standing gaps spanning millions of base pairs. The resulting sequence of chromosome 8, as well as raw data from complementary long-read sequencing technologies, are freely available from the Nature paper. Chromosome 8 is the first human autosome to be sequenced and assembled from telomere to telomere and contains only the third completed human centromere.
Director of the Center Dr. Prof. Alla Lapidus was included in the Forbes list of 10 Russian Women in Science!
Alexey Gurevich, CAB senior research fellow, has been recognized by the Russian branch of Academia Europaea for his work on QUAST and NPDtools projects. The Academy’s prizes are awarded once every several years for remarkable achievements by young Russian scientists (under 34 y.o.) in one of the six fields of study: Mathematics,
CAB junior research fellow Dmitry Meleshko received a Russian President Scholarship for young scientists (under 35 years) in prioritized economics sectors. His application describes plans for coronaSPAdes and PathRacer future development and was highly praised by the experts. This is the first member of CAB to receive this award! Congratulations!
metaFlye is a new metagenomic-specific version of the Flye long-read genome assembler (ONT and PacBio sequencing).
The paper about the assembler and its application to real and simulated metagenomic datasets is out in Nature Methods (see SPbU press releases in Russian and English). The research project is a result of a collaboration of 11 Russian and American scientists which included two members of our laboratory,
T2T Consortium presented first complete human genome assembly on T2T/HPRC Open Science Days! Polished version of the assembly can be found on github. This is exciting breakthrough for all bioinformatics community!
The fourth international conference “Bioinformatics: from Algorithms to Applications” (BiATA2020) moved online this year and was accompanied by a 2-day workshop on metagenomic data analysis. All pre-recorded talks are available online and can be found on BiATA2020 website.
We thank all speakers for presenting their great work and looking forward to the next year!
We are delighted to present novel SPAdes assembler mode — coronaSPAdes, created by our researchers Anton Korobeynikov and Dmitry Meleshko. CoronaSPAdes allows to assemble full-length coronaviridae genomes from the transcriptomic and metatranscriptomic data. For more details visit coronaSPAdes official page.
We hope that coronaSPAdes will accelerate the ongoing coronavirus research!
EMBL-EBI presented the latest version of the MGnify 5 pipeline, which now uses metaSPAdes for all metagenome assemblies. Check out new version at EMBL-EBI website here. More detailed information on the latest release can be found in the original paper.
Congratulations to Anton Korobeynikov and all members of our laboratory,
First complete genome sequence of coronavirus SARS-CoV-2 from a Russian patient was sequenced by the scientific group from Smorodintsev Research Institute of Influenza in collaboration with members of our laboratory Michael Rayko and Dmitry Antipov. The sequence, named hCoV-19/Russia/StPetersburg-3524/2020, is available via GISAID.
See more details in N+1 (in Russian)