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IgSimulator is a tool for simulation of antibody repertoire and Ig-seq library. IgSimulator is designed for testing and benchmarking tools for reconstruction of Ig repertoires.

IgSimulator generates:

    • FASTA file with reference Ig repertoire
    • FASTQ reads covering variable regions of simulated antibodies
    • Ideal repertoire corresponding to Ig-seq library in CLUSTERS.FA and RCM format (details can be found here).
    • Figures showing statistics of simulated repertoire:
base_sequences_lengths shm_positions
Histogram of simulated sequence lengths distribution. Histogram of relative SHM positions distribution. Reds bars correspond to CDR positions.

IgSimulator manual can be found here.